We would recommend against this. Although some active speakers could be used as a guitar amplifier or as an amp for another instrument, the speakers are not designed to perform in this manner and there are plenty of other products on the market that are more suitable for this application. Many people ask us if Tannoy drivers can be used in a guitar amp cabinet. Again, the could be used but they would not deliver the same performance as a speaker designed for use in a guitar cabinet, therefore we recommend looking at something a bit more suitable.