When you open a software App that uses audio, such as an internet browser, or a media player like Spotify, it takes control of your audio playback device.

This means that if you launch another App that requires the use of your audio driver, it likely will not playback. 

In this case if you’re running into an issue like no audio playing back in your DAW, the first, and most simple thing is to check and see if Exclusive Mode is enabled or not.

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