Yes, it is possible to use the Blender with Zoom, however, there are number of key things to keep in mind depending on your operating system.

When working with PC, due to windows limitations you will only be able to use input 1 of the Blender, if you wish to use more than one microphone, an instrument with a microphone or 2 instruments it is possible to do this by utilising a headphone splitter cable. Please note both will share the same input gain on the Blender.

If used with a Macbook all inputs will work normal.

Please ensure you download all necessary drivers prior to use (Windows only) and ensure you have the Blender selected as your audio input and output with your computer audio settings and Zoom audio settings.