Depending on which Expansion card you have installed will determine which driver you should use with your Windows 10 machine. 

For example if you are using a X-USB card, you will need to install the X-USB driver. 

If you are using a different Expansion card to driver (For example a X-UF card with X-Live driver) this will not work. 

You need to ensure you have the correct driver installed for each card. 
These can be found in downloads section of our Website, or on the product pages.